Great Field has suffered a setback which has ruled him out of the BoyleSports Champion Chase at Punchestown on Tuesday.
The seven-year-old, who had only returned from a 330-day absence at Navan last month, is likely to be out until the autumn.
"He's had a bit of a setback which means he can't run," said Frank Berry, racing manager to owner JP McManus.
"You'll probably won't see him until the autumn."
Trained by Willie Mullins, Great Field had been expected to be among the declared runners for the Grade One contest over two miles after taking his winning run to five.
He had seemingly booked his place with victory over Doctor Phoenix in the Webster Cup Chase, on his first start since he took the Ryanair Chase at this meeting last spring.